Iulia Alexa

Title: Correlations between the oral microbiome and systemic diseases

The human being is defined as a “superorganism” because it is made up of its own cells and microorganisms that reside inside and outside the human body. Commensal microorganisms, which are as many as ten times more numerous than the cells present in the body, perform very important functions for the host, as they contribute to host health, resist pathogens, maintain homeostasis, and modulate the immune system.

The oral cavity is one of the most important windows of interaction between the human body and the environment.

The microenvironment in different parts of the oral cavity has different microbial compositions and is influenced by complex signals between the host and external environmental factors. These processes may affect or reflect overall human health, as certain health conditions are influenced by the composition of oral bacteria, and disruption of the microbial community is correlated with certain systemic diseases. The oral microbiome cooperates with the host to reflect information about the state of immunity and metabolism through bidirectional communication in the oral cavity and systemic organs.

This presentation discusses the link between oral dysbiosis and common systemic diseases, as there is often a link between systemic health and oral health, traditionally viewed as a local ecosystem.